Trempealeau Chamber of Commerce welcomes you to explore our historic downtown and the beautiful Mississippi River. The Trempealeau Main Street Historic District has maintained its “turn of the century” architecture and has been listed on the National Register of Historic Places since 1984. Near Main Street, there are several quaint inns and hotels on the river as well as a few restaurants nearby. Only a short distance away, lie the Trempealeau bluffs, which feature hiking trails with river views, camping and picnic areas. Perrot State Park is Trempealeau’s next door neighbor.