
Welcome to the La Crosse Region!
No matter your niche, plan your stay nestled between towering bluffs and along the grand Mississippi River.
Holmen | La Crescent | La Crosse | Onalaska | Town of Campbell | West Salem
Welcome visitors! Whether you are looking for a vacation or just a long weekend, the La Crosse Region offers something for everyone. Plan your stay nestled between towering bluffs and along the grand Mississippi River. With indoor and outdoor activities, arts and culture, and a vast variety of places to eat and stay, you’re bound to enjoy the area from sunrise to sunset.
Just a Road Trip Away
Miles and drive time to the La Crosse Region
Appleton, WI 169 Miles | 3 Hours | Madison, WI 130 Miles | 2 Hours 15 min |
Chicago, IL 275 Miles | 4 Hours | Milwaukee, WI 204 Miles | 3 Hours |
Des Moines, IA 272 Miles | 4 Hours | Minneapolis/St. Paul, MN 160 Miles | 2 Hours 30 min |
Duluth, MN 238 Miles | 4 Hours 15 min | Quad Cities 188 Miles | 3 Hours 35 min |
Our Brief History
The La Crosse Region sits at the heart of the Driftless Area — one of the most geologically unique landscapes in the Upper Midwest. Unlike surrounding regions flattened by ancient glaciers, this corner of Wisconsin was untouched during the last Ice Age. The term “driftless” refers to the absence of glacial drift — those layers of rock and sediment typically left behind by moving ice. Because glaciers never reached this area, the terrain remains strikingly rugged, with dramatic bluffs, deep valleys, limestone ridges, and winding waterways shaped over millions of years. Today, the Driftless Region offers a rare glimpse into what much of the Upper Mississippi Valley once looked like, making La Crosse a one-of-a-kind destination for outdoor lovers, geology buffs, and curious travelers alike.
Straddling the Mississippi River, the Driftless Region of today spans for more than 24,000 miles across Minnesota, Wisconsin, Iowa, and Illinois. La Crosse County is one of the 18 Wisconsin counties within the realm of the Driftless and is filled with trails for hiking, rivers to fish and paddle, challenging cycling routes and much more.
The Mississippi River has influenced many lives: the Dakota, Chippewa and Hopewell cultures, and early French voyagers and European settlers’ heritage. The bluffs provide a heavily wooded habitat, leading to the Region’s initial logging industry. The La Crosse Region is filled many with historic locations that contribute to the rich culture of today. For a listing of these historic locations, check out our Visitors Guide and or visit the La Crosse County Historical Society, dedicated to the collection, preservation, display, and publication of county heritage.


Explore La Crosse
The La Crosse County Convention and Visitors Bureau (Explore La Crosse), builds awareness of the Upper Mississippi Valley region as a global tourist destination. Increasing revenue and stimulating economic development, enhancing visitor spending and overnight stays, will be realized by promoting leisure travel, conventions, sports, and events while highlighting our Region’s natural beauty and showcasing the talents of our residents for all the communities we proudly represent.


Wisconsin Great River Road
The La Crosse Region also resides along the famous Great River Road National Scenic Byway. Winding 250 miles along the Mississippi River through historic river towns, the Wisconsin Great River Road continues to link resources, people and history annually. Commonly known as the most scenic drive in America, the Great River Road is a must road trip, conveniently leading you to the stunning La Crosse Region.
Dive into Our Visitors Guide
Check out La Crosse’s Visitors Guide to explore the best attractions, dining, and events in the area!
